- The film is based on an original story by Amanda Sthers.
- Principal photography took place in May 2022 on location in Rome, Italy.
- Mafia Mamma was released in theaters on April 14, 2023, and grossed $7 million worldwide. The film was released digitally on May 2, 2023, and physical copies on June 6.
- Mafia Mamma grossed $3.5 million in the United States and Canada, and $3.5 million in other territories, for a worldwide total of $7 million.
- The film was released alongside Renfield, The Pope’s Exorcist, Suzume, and Sweetwater, the film made $866,940 on its first day and went to debut on $2 million from 2,002 theatres, finishing eighth at the box office.