- Juel Taylor’s directorial debut.
- Development on the film began in February 2019 when the screenplay was optioned from The Black List by MACRO Media.
- Brian Tyree Henry was initially attached to star as a lead but was eventually replaced by John Boyega in October 2019.
- Principal photography began in November 2020, in Atlanta, Georgia. Filming took place in Blackhall Studios and ended in April 2021.
- It premiered at the American Black Film Festival on June 14, 2023. The film began a limited theatrical release on July 14, 2023, before streaming on Netflix a week later. They Cloned Tyrone was released on July 21, 2023, on Netflix. The film received positive critical reviews, with particular praise aimed at the humor and lead cast performances.